The Evaluation of effect of Kanchanar Guggul in Sub-clinical Hypothyroidism with respect to Agnimandya

Abstract

Sub Clinical Hypothyroidism is a condition in which there is biochemical evidence of deficiency of thyroid hormone having few or no apparent clinical features of Hypothyroidism. The prevalence of Hypothyroidism in the developed world is about 4-5% and that of subclinical Hypothyroidism is about 4-15%^. According to Ayurveda, the function of thermogenesis and metabolism in the body is principally related to Agni. Any deviation in the function of Agni is called as Agnimandya. It interferes with the metabolism and thermogenesis. In consideration with the role of thyroid gland in metabolism, the term Agni can be correlated. Aim and objective: this study is aimed to explore the efficacy of Kanchanar Guggul in Sub-Clinical Hypothyroidism. Methodology: this is the randomized controlled study. Total 40 patients taken in this study and divided into two groups by lottery method. Levothyroxine 25mg at morning and kanchanar guggul 500mg twice a day was given respectively for 30 days and follow up was taken. Conclusion: Subclinical hypothyroidism is found to be more prevalent in females in the age group of 30 to 50 years.TSH level was also decreased which indicates that it acts on metabolism process. It might be required to give Kanchanar Guggul for long duration to normalize the Agni.