Pharmaceutical Modification of Kasisadi Churna to Varti and its Physicochemical Analysis

Abstract

Background: Kasisadi churna is a yoga (formulation) mentioned for treatment of kaphaja yoni vyapath (vulvo vaginal candidiasis) which is applied as lepa along with honey. But the administration of the drug through vaginal route in this form is highly discomforting. Modification of a dosage form is essential for the enhancement of efficacy, acceptability of the product and shelf life. Materials and Methods: Varti is prepared from the drugs of kasisadi churna in three methods, bhavana method (KV1), gudapaka method (KV2) and modified method (KV3) with the addition of cocoa butter as base. The prepared samples were tested for analytical parameters. Result and Discussion: Kasisadi churna can be easily modified into varti form. Preparation of KV2 was easy, gives more yield in less time and better in organoleptic features and disintegration time compared to KV1 and KV3. Conclusion: The results of the pharmaceutical and analytical study can be considered as the preliminary standards for the preparation of Kasisadi Varti.