Study on physical properties of Ayabirungaraja Karpam engaged by Traditional and Modern technique
DOI:
https://doi.org/10.47552/ijam.v12i3.1916Keywords:
Characterization, Absorption, Mucous membrane, Traditional formulation, Efficacy, Surface areaAbstract
The physical characterization is an authentic proof for the metal and mineral drug formulations used in traditional system of medicine. Now a day quality assurance is a thrust area for the evaluation of traditionally used medicinal plants and herbal formulations. In this research work, author aims to elicit traditional and modern physical characterization of Siddha formulation Ayabirungaraja karpam(ABK). It was prepared as per Siddha reputed text classical method and subjected to physical characterization traditionally such as consistency, lightness, texture, particle size, colour, odour, tactile sensation, irreversible nature and modern parameters like pH value, Loss on drying, Total ash, acid insoluble ash, water soluble ash, Bulk density, Tapped density, Zeta size, Zeta potential and BET analysis for surface area. The results reveal as per traditional trait, ABK is non-adhesive freeness, fineness and lightness which enhance absorption and assimilation of particle in body without producing any irritation to the mucous membrane of gastrointestinal tract. Modern parameter indicate the presence of organic moieties as well as mineral, acidic medium which was not favour for microbial growth , cohesive, low porosity and compaction of drug powder was confirmed. Particle size matches well with colloidal size which attached to human intestine and thus provide large surface area, thereby increase absorption of macro, micronutrients and drug. Therefore, it is concluded the drug is user friendly for human oral administration.
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