In-Silico Molecular Docking in Screening of Anti-Diabetic Therapeutics from Medicinal Plants
Keywords:Diabetes Mellitus, Diabetic Targets, Herbal Drugs, Molecular Docking, Protein
One of the most widely spreading diseases due to several lifestyle problems in the 21st century is diabetes mellitus. The management of diabetes mellitus is very important and essential. Plants are natural reservoir of many medicinal value added components help to overcome many chronic disorders including diabetes mellitus. Herbal drugs are prescribed in treatment of diabetes mellitus due to their good effectiveness, fewer side effects in clinical experience and relatively low costs. Screening of antidiabetic therapeutics is very important and essential for effective management of diabetes mellitus. Many researchers have worked on extraction, isolation, characterization of extracts and bioactive fractions from medicinal plant also they have established profile and data of interaction of active components against various targets and enzymes of diabetes mellitus using In-silico molecular docking tools. Molecular docking is an important computational tool to predict the plausible interactions between the drug and protein in a non-covalent fashion. Extensive in silico docking procedures have been carried out to examine whether the compound is a good ligand with diabetic targets. In the present review article we have thoroughly screened research articles published in various scientific, indexed, national and international journals on In-silico molecular docking based screening of Anti-Diabetic potentials and therapeutics from medicinal plant and extensively presented.
How to Cite
The author hereby transfers, assigns, or conveys all copyright ownership to the International Journal of Ayurvedic Medicine (IJAM). By this transfer, the article becomes the property of the IJAM and may not be published elsewhere without written permission from the IJAM.
This transfer of copyright also implies transfer of rights for printed, electronic, microfilm, and facsimile publication. No royalty or other monetary compensation will be received for transferring the copyright of the article to the IJAM.
The IJAM, in turn, grants each author the right to republish the article in any book for which he or she is the author or editor, without paying royalties to the IJAM, subject to the express conditions that (a) the author notify IJAM in advance in writing of this republication and (b) a credit line attributes the original publication to IJAM.