Preliminary pharmaceutico-analytical study of Mukhadooshikaharalepa Churna

Abstract

Introduction: Lepa is a bahirparimarjana chikitsa that helps in bringing samyata in sthanika dosha and dhatu. Many lepa are mentioned in Ayurveda pharmaceutics for the treatment of mukhadooshika. Among it, one is a combination of Lodhra, Kustumburu, Vacha, Vatapallava, and Narikelashuktya. Mukhadooshika is a type of kshudraroga, featuring the formation of pidaka on face. The symptoms of mukhadooshika resembles with acne vulgaris. Aim: An attempt is made to analyze the physico-chemical parameters of the mukhadooshikahara lepa churna. Materials and methods: The pharmaceutical preparation is easy and simple with easily available ingredients. The organoleptic characters like appearance, odour, taste and physico-chemical parameters like pH, total ash. Water Soluble ash, Alcohol soluble extractives, Water soluble extractives, loss on drying and HPTLC were carried out. Observations and results: The obtained results were discussed in the present paper. Discussion and conclusion: Mukhadooshikahara lepa churna is a simple preparation and can be prepared by easily available drugs. HPTLC fingerprinting at different wavelengths was carried out. At 254 nm, 366nm and 620nm 11, 8 and 10 peaks were found with different retention factor starting from 0.02 to 0.80, 0.03 to 0.096 and 0.07 to 0.80respectively. The analytical study findings can be taken as a preliminary standard for mukhadooshikahara lepa churna.