Evaluation of the Antimicrobial efficacy of a novel polyherbal extract against Streptococcus Mutans: An in-vitro study
Keywords:Streptococcus mutans, Polyherbal, Antimicrobial, Triphala, Terminalia Chebula, Terminalia bellerica, Emblica officinalis, Glycyrrhiza glabra, Curcuma longa, Acorus Calamus
Aim: The present study was done to assess the antibacterial efficacy of a polyherbal extract against Streptococcus mutans (S. mutans) in-vitro. Materials and methods: In the current study, the ethanolic extracts of Haritaki, Bhibitak, Amalaki, Yashtimadhu, Haridra and Vacha were subjected to microbiological assay. The microbial growth inhibitory potential of the polyherbal extract was determined by using the agar disc diffusion method. Results: Mean zone of inhibition of polyherbal extract mix against S. mutans at 48 hours was 24mm. Minimum Inhibitory Concentration and Minimum Bactericidal Concentration of polyherbal extract mix on S. mutans was 0.1gm/mL and 0.2gm mg/mL respectively. Conclusion: The polyherbal extract had antimicrobial efficacy against streptococcus mutans. This polyherbal extract could have potential clinical implications. Clinical significance: as many chemical agents used for prevention of dental caries might have long term adverse effects, use of plant based products could be an excellent treatment alternative. This polyherbal extract possesses antibacterial properties against streptococcus mutans and hence could be used for prevention of dental caries. The herbs used in the study are easily available, economically feasible and are being used since time immemorial.
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