Hypolipidemia activity testing protocol or Guizotia Abyssinica Cass. seed oil: An Experimental study report

Authors

  • Bani Shashikala B
  • Mallya Suma V
  • Bhat Sudhakara

DOI:

https://doi.org/10.47552/ijam.v12i4.2296

Keywords:

Guizotia abyssinica Cass, Hyperlipidemia, Experiment, Wistar albino rats, Cholesterol, Histopathology

Abstract

Hyperlipidemia is characterized by increased level of cholesterol in the form of low-density lipoprotein (LDL), chylomicrons, VLDL. Guizotia abyssinica Cass (Ramtil) seeds are one among the sources for the edible oil, which are low in saturated fat, cultivated commonly in Northern part of Karnataka. Materials and Methods: Guizotia abyssinica Cass (Ramtil) seeds were collected authenticated seed oil extracted by Cold compression method. The experiment carried out in Wistar albino rats, inducing Hyperlipidemia by HFD, along with administration of test drugs (Guizotia abyssinica Cass. seed oil Single and double dose) and Standard Atorvastatin.  Results & Discussion: G. abyssinica Cass seed oil found to decrease total cholesterol and LDL. Even not showed significant increase in HDL. Protective action over the Liver, Kidney and heart through histopathological study exhibit its safety aspect. Conclusion: G. abyssinica Cass seed oil in HFD induced Hyperlipidemia found effective and safe.

Author Biographies

Bani Shashikala B

PhD Scholar, Department of Dravyaguna, Sri Dharmasthala Manjunatheshwara College of Ayurveda Kuthpady, Udupi, Karnataka. India.

Mallya Suma V

Associate Professor, Department of Dravyaguna, Sri Dharmasthala Manjunatheshwara College of Ayurveda Kuthpady, Udupi, Karnataka. India.

Bhat Sudhakara

Research Officer, SDM Centre for Research in Ayurveda and Allied sciences Kuthpady, Udupi. India.

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Published

31-12-2021

How to Cite

B, B. S., V, M. S., & Sudhakara, B. . (2021). Hypolipidemia activity testing protocol or Guizotia Abyssinica Cass. seed oil: An Experimental study report . International Journal of Ayurvedic Medicine, 12(4), 938–942. https://doi.org/10.47552/ijam.v12i4.2296

Issue

Vol. 12 No. 4 (2021): October - December 2021

Section

Research Articles

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