Management of Acromegaly associated Late-onset hypogonadism by Siddha medicine: A case report

Abstract

Male Hypogonadism is the condition diagnosed in men with signs and symptoms of testosterone deficiency. Hypogonadism may be further classified as primary or secondary caused due to organic or functional pathology. This classification has significant therapeutic implications for instituting gonadotropin therapy to restore testosterone levels, spermatogenesis and so fertility is possible in secondary hypogonadism but not in primary hypogonadism. Testosterone replacement therapy (TRT) remains the mainstay and primary therapeutic option in the treatment of hypogonadism. In this case report, we discuss acromegaly associated Late-onset hypogonadism (LOH) treated successfully with Siddha medicine regimen on screening with Androgen deficiency in aging male (ADAM’s) Questionnaire, laboratory investigation of total testosterone level and evaluated the patient’s quality of life using the Aging Male’s symptoms scale (AMS) for prognosis. Siddha treatment regimen such as Poonaikali vidhai chooranam with Amukkra chooranam was administered for one year. Total testosterone level improved from 70 ng/dl to 172 ng/dl and ADAM’s score reduced from 49 to 27, while AMS score reduced from 5 to 1 indicating an alternative ray of hope to TRT.