Pharmaceutical Analysis of Kanchanara & Nano Kanchanara Stem Bark Powder in Hypothyroidism

Abstract

Ayurveda is a holistic science dealing with all aspects of human life. Bauhinia variegata (Kanchanar) is a medicinal tree that is widely used in Ayurvedic indegenious medicine system. Herbal medicines have a long therapeutic history; serving many of the health needs of large population of the world. Maintaining quality standards of herbal drugs is the need of today because of its increasing demand. However, due to the wide range of chemical components involved, quality management and assurance remain a concern for herbal medicines. In Ayurvedic texts, several formulations have been mentioned in Galganda and Gandamala where Kanchanara being the main component. As most of the formulations mentions the use of stem bark, the pulverized powder of the same was prepared. Later by the use of High Energy Ball Milling Methodology (HEBM) fine powder of Kanchanara was converted to Nano Kanchanara stem bark powder. This Nano Kanchanara stem bark powder was seal packed to maintain its shelf life. Kanchanara and Nano Kanchanara stem bark powder were subjected to organoleptic analysis, phytochemical and qualitative analysis to detect the presence of various functional groups, and to high performance thin layer chromatography (HPTLC) examination by optimizing the solvent systems. The investigations are revealed mainly.