Development and Evaluation of Antimicrobial Activity of Durva Nishadi Ointment: In-vitro Study

Authors

  • Geeta Gadad
  • Hiremath R S
  • Bolmal U B

Keywords:

Antimicrobial activity, Durva Nishadi ointment, Microbial infection, Disc diffusion method

Abstract

Background: Synthetic antimicrobials are often associated with adverse effects as a result, there is need for the use of alternate herbal medicines is increasing with their easy availability, safety, cost effectiveness and therapeutic potentiality. In this present study Durva Nishadi Ointment was developed from Durva nishadi Yoga described in Ayurvedic classics as a Lepa (topical application) against microbial diseases like Kandu (Pruritis), Pama (Scabies), Dadru (Tinea/ Ringworm infection), Sheetapitta (Urticarial rashes) and Krimi (Microbial infections).

Result: The developed Durva Nishadi ointment has highly significant antifungal activity than the antibacterial activity. Antifungal activity of 20% ointment against Candida albicans was 28mm of zone of inhibition at 25 μg/ ml, and for Aspergillus niger 15 mm of zone of inhibition at 5 μg/ ml, which are highly comparable with the synthetic standard drug used for the antifungal activity i.e. Fluconazole.

 

Abbreviations

MIC - Minimum inhibitory concentration, MHA - Muller-Hinton Agar

 

Author Biographies

Geeta Gadad

Assistant Professor, Department of Rasashastra and Bhaishajya Kalpana, KAHER’S Shri B M Kankanawadi Ayurveda Mahavidhyalaya Shahapur, Belagavi, Karnataka. India. 

Hiremath R S

Professor, Department of Rasashastra and Bhaishajya Kalpana, KAHER’S Shri B M Kankanawadi Ayurveda Mahavidhyalaya Shahapur, Belagavi, Karnataka. India. 

Bolmal U B

Associate Professor, Department of Pharmaceutics, KLEU’s College of Pharmacy Belagavi, Karnataka. India.

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Published

08-07-2022

How to Cite

Gadad, G., R S, H., & U B, B. (2022). Development and Evaluation of Antimicrobial Activity of Durva Nishadi Ointment: In-vitro Study. International Journal of Ayurvedic Medicine, 13(2), 400–405. Retrieved from https://ijam.co.in/index.php/ijam/article/view/2573

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Section

Research Articles