Development and Evaluation of Antimicrobial Activity of Durva Nishadi Ointment: In-vitro Study
DOI:
https://doi.org/10.47552/ijam.v13i2.2573Keywords:
Antimicrobial activity, Durva Nishadi ointment, Microbial infection, Disc diffusion methodAbstract
Background: Synthetic antimicrobials are often associated with adverse effects as a result, there is need for the use of alternate herbal medicines is increasing with their easy availability, safety, cost effectiveness and therapeutic potentiality. In this present study Durva Nishadi Ointment was developed from Durva nishadi Yoga described in Ayurvedic classics as a Lepa (topical application) against microbial diseases like Kandu (Pruritis), Pama (Scabies), Dadru (Tinea/ Ringworm infection), Sheetapitta (Urticarial rashes) and Krimi (Microbial infections).
Result: The developed Durva Nishadi ointment has highly significant antifungal activity than the antibacterial activity. Antifungal activity of 20% ointment against Candida albicans was 28mm of zone of inhibition at 25 μg/ ml, and for Aspergillus niger 15 mm of zone of inhibition at 5 μg/ ml, which are highly comparable with the synthetic standard drug used for the antifungal activity i.e. Fluconazole.
Abbreviations
MIC - Minimum inhibitory concentration, MHA - Muller-Hinton Agar
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 International Journal of Ayurvedic Medicine
This work is licensed under a Creative Commons Attribution 4.0 International License.
The author hereby transfers, assigns, or conveys all copyright ownership to the International Journal of Ayurvedic Medicine (IJAM). By this transfer, the article becomes the property of the IJAM and may not be published elsewhere without written permission from the IJAM.
This transfer of copyright also implies transfer of rights for printed, electronic, microfilm, and facsimile publication. No royalty or other monetary compensation will be received for transferring the copyright of the article to the IJAM.
The IJAM, in turn, grants each author the right to republish the article in any book for which he or she is the author or editor, without paying royalties to the IJAM, subject to the express conditions that (a) the author notify IJAM in advance in writing of this republication and (b) a credit line attributes the original publication to IJAM.
