Antimicrobial activity and Quality Control Parameters of Talicati Vatakam - A Classical Siddha Drug

Authors

  • Rajesh Allu
  • Padmini D
  • Indhumathi M
  • Sujith Thatipelli
  • Achintya Kumar Mandal
  • Ganesan R
  • Shakila R

DOI:

https://doi.org/10.47552/ijam.v13i2.2600

Keywords:

Talicati Vatakam, Staphylococcus aureus, Respiratory, Antimicrobial, Standardization

Abstract

Tāḷicāti vaṭakam (TSV), a polyherbal siddha drug was chosen, it was screened for antimicrobial study and also subjected to standardization parameters. The ingredients were procured, authenticated and prepared the drug as per standard operating procedure. The ethanolic extract of TSV was screened for nine bacteria and two fungi. Then the drug was investigated for the phytochemical profile, physicochemical parameters, thin layer chromatographic  photo documentation (TLC), high-performance thin-layer chromatography (HPTLC) finger print profile. Antimicrobial assay revealed  inhibitory activity against all test pathogens. TLC under UV  showed 8 bands at short wavelength, 13 bands at long wavelength; 8 bands showed post derivatization with vanillin Sulphuric acid reagent. The present investigation concluded that the siddha herbal preparation of TSV have great potential on antimicrobial against pathogens. This siddha formulation can be used to prevent the bacterial and fungal infections and the standards could be used for quality control of the drug.

Author Biographies

Rajesh Allu

Research Assistant (Chemistry), Siddha Central Research Institute, Central Council for Research in Siddha, Ministry of AYUSH, Government of India, Anna Hospital Campus, Arumbakkam, Chennai. India.

Padmini D

Lab Technician, Siddha Central Research Institute, Central Council for Research in Siddha, Ministry of AYUSH, Government of India, Anna Hospital Campus, Arumbakkam, Chennai. India.

Indhumathi M

PG Scholar, Valliammal College for Women, Chennai. India.

Sujith Thatipelli

Research Assistant (Chemistry), Siddha Central Research Institute, Central Council for Research in Siddha, Ministry of AYUSH, Government of India, Anna Hospital Campus, Arumbakkam, Chennai. India.

Achintya Kumar Mandal

Assistant Research Officer (Chemistry), Siddha Central Research Institute, Central Council for Research in Siddha, Ministry of AYUSH, Government of India, Anna Hospital Campus, Arumbakkam, Chennai. India.

Ganesan R

Assistant Director (Biochemistry), Department of Biochemistry, Siddha Central Research Institute, Central Council for Research in Siddha, Ministry of AYUSH, Government of India, Anna Hospital Campus, Arumbakkam, Chennai. India.

Shakila R

 Research Officer (Chemistry) Department of Chemistry, Siddha Central Research Institute, Central Council for Research in Siddha, Ministry of AYUSH, Government of India, Anna Hospital Campus, Arumbakkam, Chennai. India.

Downloads

Published

2022-07-08

How to Cite

Allu, R. ., D, P., M, I., Thatipelli, S., Mandal, A. K. ., R, G., & R, S. (2022). Antimicrobial activity and Quality Control Parameters of Talicati Vatakam - A Classical Siddha Drug. International Journal of Ayurvedic Medicine, 13(2), 463–468. https://doi.org/10.47552/ijam.v13i2.2600

Issue

Vol. 13 No. 2 (2022): April-June 2022

Section

Research Articles

License

Copyright (c) 2022 International Journal of Ayurvedic Medicine

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

The author hereby transfers, assigns, or conveys all copyright ownership to the International Journal of Ayurvedic Medicine (IJAM). By this transfer, the article becomes the property of the IJAM and may not be published elsewhere without written permission from the IJAM.

This transfer of copyright also implies transfer of rights for printed, electronic, microfilm, and facsimile publication. No royalty or other monetary compensation will be received for transferring the copyright of the article to the IJAM.

The IJAM, in turn, grants each author the right to republish the article in any book for which he or she is the author or editor, without paying royalties to the IJAM, subject to the express conditions that (a) the author notify IJAM in advance in writing of this republication and (b) a credit line attributes the original publication to IJAM.

https://creativecommons.org/licenses/by-nc-sa/4.0/