Analytical standardization of Shleshmantaka Agad
Keywords:Shleshmantaka Agad, Standardization, Physicochemical, Phyto-chemical
Background: To counter-act the action of visa,(poison) ancient Acharyas have mentioned the different types of Agada. Though Acharyas have mentioned various types of potent Agadas in various poisoning conditions, still these Agadas have neither undergone analytical study nor animal experiment. Shleshmantaka Agad is one of the drug remedy mentioned in Shushrut Samhita, kalpa sthan used for treatment of snake bite poisoning. Aim: In present work an attempt has been made to standardize Shleshmantaka Agad. Material & Methods: Physicochemical parameter was tested by Loss on drying, Acid insoluble Ash, Total ash value, Water & Alcohol soluble Extractive Value, HPTLC was used for phytochemical analysis. Result: In analytical study of Shleshmantaka Agad obtained value of Loss on drying, Total ash value, Acid insoluble Ash ,Water & Alcohol soluble Extractive Value are 12%, 10%, 2%, 13%, 1% respectively and in HPLC major constitute phytoamines was detected. Conclusion: Analytical findings of present study can be considered as reference standard for SA. As Shleshmantaka Agada is a combination of many phyto-constitutes but major constituent are phytoamines which may be possesses anti-snake venom property.
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