Treatment of early stage diabetic nephropathy using Siddha drug Sirupeelai kudineer - Single Case Study
Keywords:Siddha, Diabetic Nephropathy, Sirupeelai kudineer, Microalbumin, eGFR, Serum creatinine
Background: Nephropathy is one of the major micro-vascular complications of Diabetes
Mellitus, which can be detected in the earlier stage by the investigation of urinary
microalbumin excretion level, estimation of ACR and GFR. The Siddha drug Sirupeelai
Kudineer indicated for the complications of Diabetes Mellitus is selected for this Case study.
The efficiency of the drug was reported by measuring the change in Renal function over the
period of study and the KD QOL assessment. Case description: A male patient of 62 years
with the history of DM and hypertension since 20 years came to the hospital with complaints
of bilateral pedal oedema, general weakness, frequent nocturnal micturition and weariness of
limbs since last two months. His renal profile and glycaemic index was deranged (Serum
Creatinine -1.42 mg/dl; Blood Urea -54.3 mg/dl; Urine Micro albumin -99.45mg/L; Urine
Creatinine -74.8 mg/dl; ACR -15.02 mg/mmol; eGFR - 64.5 ml/min; BSL (Fasting) -157
mg/dl; BSL (Postprandial) -289 mg/dl). Patient was taking certain oral allopathic medicines
and injection huminsuline 30/ 70 in the dose of 35 units before lunch, and 30 units before
dinner subcutaneously. As per Siddha concept his three humours deranged and seen with the
Clinical features of Madhumega roga avathaigal and Neeradaippu. He was given Siddha
medicine Sirupeelai kudineer-120ml twice a day for the period of one month. Significant
relief in symptoms and improvement in certain renal parameters was noted in the subject.
Conclusion: The clinical and laboratory parameters in this case study suggest that this drug
may be used along with other allopathic drugs in the treatment of Diabetic nephropathy
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