Single Blind Randomized Control Clinical Study to Assess the Effect of Cow-Ghee On Lipid Profile and Blood Glucose in Healthy Volunteers

Abstract

Ayurveda consider cow ghee as healthiest source of dietary fat and have rejuvenating property, improves memory and strengthens nervous, eyes and protects the body from various diseases by balancing all three Doshas (Vata, Pitta and Kaph) and advocates it’s use in daily diet to maintain health. Though, today concept of healthy eating has become synonym to avoid ghee. Aim: To assess the efficacy of Cow Ghee on Lipid Profile and Blood Sugar levels in Healthy Volunteers. Materials and methods: This was a Single blind randomized control clinical study. 60 healthy volunteers (30 in each group) between the age group 25-45 years were randomly selected. FBS was assessed based on WHO Guideline and Complete lipid profile was assessed based on ATP III Guideline.  Statistical analysis used:  result was assessed using Paired and unpaired t test with the help of Graph Pad InStat-3 software. Results: The slight increase in FBS, TC, TGs, VLDL, and HDL was recorded with mean difference 2.054, 2.91 (p = 0.4376), 21.568 (p = 0.0024), 4.141 (p = 0.0039), and 2.068 (p=0.0483) respectively compare to mean difference 10.260, 5.835 (p=0.2348), 16.88 (p=0.0297), 3.39 (p = 0.0274), and no change in HDL in placebo control group. While decrease in LDL by mean difference 3.291 (p = 0.3786) was recorded in cow ghee group compare to increase in mean difference 1.497 (p = 0.7844) in placebo control group. Conclusion: study reveals no adverse effect of consumption of 15-gram cow ghee daily for 45 days on lipids and FBS.