Accelerated Stability Study of Kailas Jeevan – A Proprietary Ayurvedic formulation

Authors

  • Vedantam Giridhar
  • Veena B Kupati
  • Gundakalle M B
  • Ajit Lingayat
  • Divya Khare
  • Vedhas M Kolhatkar

DOI:

https://doi.org/10.47552/ijam.v14i4.4068

Keywords:

Stability, Kailas Jeevan, Accelerated stability study, Shelf life

Abstract

Background: Stability studies are the test to assess the shelf life of the Ayurvedic proprietary medicines. Govt. of India made mandatary test for licencing and renewal of licencing of the proprietary medicine. Accelerated stability studies, testing interval of 0,3 and 6 months.  Kailas Jeevan is a proprietary semisolid dosage form prepared in GMP approved Ayurveda Sumshodanalaya (P) Pvt. Ltd. Dhayri, Pune. It is indicated in Constipation, Cracked heels, Wounds, Pimples, Burns etc.

Aims and Objectives: To evaluate the shelf life of Kailas Jeevan through accelerated stability study. Materials and Methods: The formulation was prepared in the GMP approved pharmacy. Shelf life of product was evaluated by assessing in changes in physicochemical, Microbial and quantification profiles, after keeping it in stability chamber at specific temperature (40±2°C) and relative humidity (75±5%). Analysis was carried out at the intervals of 0, 1, 3, 6, 9,12, 18 and 24 months. Average 25% degradation time was calculated to find the shelf life as per the Ayurvedic Pharmacopoea of India, Part I Vol ix guidelines. Results and Conclusion: The parameters assessed in accelerated study of Kailas Jeevan, was shown under limits till 24 months. Based on multiplication factor shelf life of Kailas Jeevan is 7.02 year.

Key Words: Stability, Shelf life, Kailas Jeevan, Accelerated stability study

 

Author Biographies

Vedantam Giridhar

Associate Professor, Department of Dravyaguna, Central Research Facility, KAHER Shri BMK Ayurveda Mahavidyalaya, Belagavi, Karnataka. India.

Veena B Kupati

Assistant Professor, Department Rasashastra and Bhaishajya Kalpana,  Central Research Facility, KAHER Shri BMK Ayurveda Mahavidyalaya, Belagavi, Karnataka. India.

Gundakalle M B

Associate Professor, Department of Agada Tantra, Central Research Facility, KAHER Shri BMK Ayurveda Mahavidyalaya, Belagavi, Karnataka. India.

Ajit Lingayat

Associate Professor, Department of Dravyaguna, Central Research Facility, KAHER Shri BMK Ayurveda Mahavidyalaya, Belagavi, Karnataka. India.

Divya Khare

Associate Professor, Department of Dravyaguna, Central Research Facility, KAHER Shri BMK Ayurveda Mahavidyalaya, Belagavi, Karnataka. India.

Vedhas M Kolhatkar

Director, Ayurveda Sumshodanalaya (P) Pvt. Ltd. Dhayri, Pune. India.

 

 

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Published

07-01-2024

How to Cite

Vedantam , G. ., Kupati, V. B., M B, G. ., Lingayat, A. ., Khare, D. ., & Kolhatkar, V. M. (2024). Accelerated Stability Study of Kailas Jeevan – A Proprietary Ayurvedic formulation. International Journal of Ayurvedic Medicine, 14(4), 1007–1014. https://doi.org/10.47552/ijam.v14i4.4068

Issue

Vol. 14 No. 4 (2023): October - December 2023

Section

Research Articles

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