Effectiveness of Nimbasava Nasya with Sigru Beeja in Acute Exacerbation of Chronic Rhino Sinusitis - A Comparative Clinical Trial


  • Neethu Kesavan
  • Thrijil Krishnan EM
  • Sreeja Sukesan




Chronic rhinosinusitis, Asava Nasya, Nimbasava, Sigru beeja


Chronic Rhinosinusitis is defined as a group of disorders characterized by inflammation of the mucosa of the nose and paranasal sinuses lasting for more than 12 weeks.  Acute exacerbation of Chronic Rhinosinusitis is defined as a sudden worsening of symptoms in a patient who has chronic sinusitis. According to the science of Ayurveda, Dushta Pratisyaya condition, is in proximity to chronic sinusitis. Asava (fermented formulation) is mentioned for Virechana Nasya (type of Errhine therapy).  Nimbasava is a formulation of Asava Kalpana prepared with Guggulu Tikthaka Gritha Yoga explained in Vaatavyadhi Chikitsa. Sigrubeeja (seed of Moringa Oleifera) and Saindhava (rock salt) are explained among Shirovirechana Gana (a group of medicines that can be used for nasal administration). The study was conducted on 30 patients of chronic sinusitis who were randomly divided into two groups and were given treatment for 7 days and follow-up after for 3 months. Out of two groups, 15 patients were given Virechana Nasya with Nimbasava, Sigru Beeja, and Saindhava for 7 days. The other 15 patients were treated as a standard control group and given the modern conventional management with Amoxicillin Clavulanate 500 mg, Fluticasone nasal spray, and Otrivin nasal drops for 7 days. The statistical analysis of data was done with the Wilcoxon Signed Rank Test and Mann-Whitney U test. During this trial, it was observed that Nimbasava Nasya with Sigrubeeja is effective in acute exacerbation of Chronic Rhinosinusitis. Pain relieving action of this Nasya was statistically highly significant. It was also found that the effectiveness of Nasya is more in reducing the recurrence of acute exacerbations of Chronic Rhinosinusitis.

Author Biographies

Neethu Kesavan

Research Officer (Ay.), Regional Ayurveda Research Institute for Mineral and Marine Medicinal  Resources, Goa, CCRAS, Ministry of AYUSH. India. 

Thrijil Krishnan EM

Assistant Professor, Department of Rachana Sharir, All India Institute of Ayurveda, Goa. India. 

Sreeja Sukesan

Professor & HOD, Department of Shalakya Tantra, Government Ayurveda College, Tripunithura, Kerala. India. 




How to Cite

Kesavan, N., Krishnan EM, T. ., & Sukesan, S. . (2024). Effectiveness of Nimbasava Nasya with Sigru Beeja in Acute Exacerbation of Chronic Rhino Sinusitis - A Comparative Clinical Trial. International Journal of Ayurvedic Medicine, 15(2), 426–430. https://doi.org/10.47552/ijam.v15i2.4680



Research Articles