Effect of Meshashrungi Patra vati and Ajashrungi Patra vati in management of Type 2 Diabetes mellitus-A Randomised, Single blind, Clinical Study

Abstract

India is known as the Diabetic capital of the world due to the increasing Diabetic population. Diabetes is increasing day by day because of lifestyle changes. As per the WHO statistics around 2 million deaths occur each year because of diabetes. Hence there is a serious concern to find an effective and safe medicine for the treatment of diabetes. Many herbal drugs have been researched and found to be effective in controlling the diabetes. One of such herbs is Gymnema sylvestre (Retz.) R.Br. ex Sm. (GS). It is equated with Meshashrungi, mentioned in the Ayurvedic texts. Ajashrungi (Pergularia daemia (Forssk.) Chiov.) (PD) is also taken as a substitute for Meshashrungi. So, to find out the efficacy of both the drugs in the management of diabetes, the present work is taken up. It was a Prospective, Randomised, Single blind, Comparative Clinical Study. A total of 40 subjects were randomised into two groups with 20 subjects each. Group A were administered Meshashrungi patra vati and Group B were administered Ajashrungi patra vati for a period of 60 days with a follow up for every 15 days. Assessment was done based on changes seen in subjective and objective Parameters. Significant changes were observed in both the groups before and after the treatment, but when compared between the groups there was no significant difference. This indicates that both the drugs are equally efficacious in the management of diabetes mellitus. Hence, both the drugs can be used as substitutes for the management of diabetes mellitus.