A community-based study for evaluation of Ayurvedic formulations in the management of Osteoarthritis Knee

Authors

  • Sunita Mata Research Officer (Ay.), Central Council for Research in Ayurvedic Sciences (CCRAS), D-Block, Janakpuri Institutional Area, Janakpuri, New Delhi. India. https://orcid.org/0000-0002-4878-7602
  • Deepa Makhija Assistant Director (Ay.), Central Council for Research in Ayurvedic Sciences (CCRAS), D-Block, Janakpuri Institutional Area, Janakpuri, New Delhi. India. https://orcid.org/0000-0003-1607-5966
  • Aparna Manathottathil Consultant (Ay.), Central Council for Research in Ayurvedic Sciences (CCRAS), D-Block, Janakpuri Institutional Area, Janakpuri New Delhi. India. https://orcid.org/0009-0006-1551-0611
  • Rakesh Kumar Rana Statistical Officer, Central Council for Research in Ayurvedic Sciences (CCRAS), D-Block, Janakpuri Institutional Area, Janakpuri, New Delhi. India. https://orcid.org/0000-0002-3115-0701
  • Anukampa Singh Senior Research Fellow (Statistics), Central Council for Research in Ayurvedic Sciences (CCRAS), D-Block, Janakpuri Institutional Area, Janakpuri, New Delhi. India.
  • Arunabh Tripathi Statistical Officer, Central Council for Research in Ayurvedic Sciences (CCRAS), D-Block, Janakpuri Institutional Area, Janakpuri, New Delhi. India. https://orcid.org/0000-0001-7235-4236
  • Sandip Kumar Research Officer (Ay.), Central Ayurveda Research Institute, Upper Mall Rd, Bharpur Garden Colony, Patiala, Punjab. India.
  • Alok Kumar Srivastava Research Officer (Ay.), Regional Ayurveda Research Institute, 21/1112, Indira Nagar Rd, Sector 21, Indira Nagar, Lucknow, Uttar Pradesh. India.
  • Amit Kumar Research Officer (Ay.), Regional Ayurveda Research Institute, Amkhoh, Gwalior, Madhya Pradesh. India.
  • Sai Prasad AJV Research Officer (Ay.), Regional Ayurveda Research Institute, HJ4X+7GC, New, Rajiv Nagar, Payak Puram, Vijayawada, Andhra Pradesh. India.
  • Sekhar Namburi UR Regional Ayurveda Research Institute, KDK College Rd, Near Gharkul Parisar, Nandanvan, Nagpur, Maharashtra. India.
  • Rahul Ghuse Research Officer (Ay.), Regional Ayurveda Research Institute, 8J82+4GQ, Gairi Gaon, Upper Tadong, Tadong, Gangtok, Sikkim. India.
  • Gopesh Sharma Research Officer (Ay.), Regional Ayurveda Research Institute, QRGF+PV3, Dina Nagar, Upper Barnai, Jammu, Jammu and Kashmir. India.
  • Kavita Vyas Research Officer (Ay.), Regional Ayurveda Research Institute, M2FW+FHV, Bhakda Beas Management Board Colony, Pandoh, Himachal Pradesh. India.
  • Parth Dave Central Council for Research in Ayurvedic Sciences (CCRAS)
  • Praveen Kumar KS Research Officer (Ay.), Central Ayurveda Research Institute, Borsojai, Beltola, Guwahati. India.
  • Neelam Singh Research Officer (Ay.), Regional Ayurveda Research Institute, Amkhoh, Gwalior, Madhya Pradesh. India.
  • Bharati PL Research Officer (Ay.), Central Ayurveda Research Institute, Borsojai, Beltola, Guwahati. India.
  • Sanjiv Kumar Research Officer (Ay.), Central Ayurveda Research Institute, Upper Mall Rd, Bharpur Garden Colony, Patiala, Punjab. India.
  • Kamble Pallavi Namdev Research Officer (Ay.), Regional Ayurveda Research Institute, 21/1112, Indira Nagar Rd, Sector 21, Indira Nagar, Lucknow, Uttar Pradesh. India.
  • Shyam Babu Research Officer (Ay.), Regional Ayurveda Research Institute, Amkhoh, Gwalior, Madhya Pradesh. India.
  • Midhuna Mohan Research Officer (Ay.), Regional Ayurveda Research Institute, HJ4X+7GC, New, Rajiv Nagar, Payak Puram, Vijayawada, Andhra Pradesh. India.
  • Reddy RG Research Officer (Ay.), Regional Ayurveda Research Institute, KDK College Rd, Near Gharkul Parisar, Nandanvan, Nagpur, Maharashtra. India.
  • Prashant Shinde Research Officer (Ay.), Regional Ayurveda Research Institute, KDK College Rd, Near Gharkul Parisar, Nandanvan, Nagpur, Maharashtra. India.
  • Sahu SK Research Officer (Ay.), Regional Ayurveda Research Institute, 8J82+4GQ, Gairi Gaon, Upper Tadong, Tadong, Gangtok, Sikkim. India.
  • Aaditya Shah Research Officer (Ay.), Regional Ayurveda Research Institute, QRGF+PV3, Dina Nagar, Upper Barnai, Jammu, Jammu and Kashmir. India.
  • Chris Antony Research Officer (Ay.), Regional Ayurveda Research Institute, M2FW+FHV, Bhakda Beas Management Board Colony, Pandoh, Himachal Pradesh. India.
  • Summed Paikrao Research Officer (Ay.), Regional Ayurveda Research Institute, Block A & D, second floor, Bahumali Bhavan, Girdharnagar, Asarwa, Ahmedabad, Gujarat. India.
  • Abha Sharma Consultant (Ay.), Central Council for Research in Ayurvedic Sciences (CCRAS), D-Block, Janakpuri Institutional Area, Janakpuri, New Delhi. India. https://orcid.org/0000-0001-9413-9131
  • Vandana Joshi Senior Research Fellow (Ay.), Central Council for Research in Ayurvedic Sciences (CCRAS), D-Block, Janakpuri Institutional Area, Janakpuri, New Delhi. India. https://orcid.org/0009-0008-2146-4839
  • Bhogavalli Chandrasekhara Rao Assistant Director (Ay.), Central Council for Research in Ayurvedic Sciences (CCRAS), D-Block, Janakpuri Institutional Area, Janakpuri, New Delhi. India.
  • Narayanam Srikanth Deputy Director General (Ay.), 18. Central Council for Research in Ayurvedic Sciences (CCRAS), D-Block, Janakpuri Institutional Area, Janakpuri, New Delhi. India.
  • Rabinarayan Acharya Director General, Central Council for Research in Ayurvedic Sciences (CCRAS), D-Block, Janakpuri Institutional Area, Janakpuri, New Delhi. India.

DOI:

https://doi.org/10.47552/ijam.v15i4.5021

Keywords:

Osteoarthritis, Sandhigata Vata, Yograj Guggulu, Ashwagandha Churna, Narayana Taila

Abstract

Background: Osteoarthritis (OA) of the knee is a major public health concern that leads to pain, disability and decreased quality of life. A similar condition has been described in Ayurveda under the name Sandhigata Vata which is caused by vitiation of Vata in the body. Objectives: Evaluation of the effectiveness and tolerability of Yograj Guggulu, Ashwagandha Churna, and Narayana Taila in OA knee. Materials and methods: The study was a prospective, multi-center, non-controlled interventional, community-based study conducted in 10 centres in India. 493 participants of any gender aged between 40 to 65 years & diagnosed with OA knee as per the diagnostic criteria American College of Rheumatology (2012), were enrolled in the study considering selection criteria. Ayurvedic formulations, Yograj Guggulu & Ashwagandha Churna were administered orally along with the local application of Narayana Taila twice daily for 12 weeks. The assessment was carried out on 28th, 56th, 84th and 112th day for any changes in the outcome measures. Results: The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) total score, the WOMAC sub-scores for pain, stiffness and difficulty in physical activity, the Visual Analogue Scale (VAS) score for pain and the disease-specific symptoms were significantly decreased throughout treatment and during follow-up without intervention. Conclusion: The study demonstrates that the Ayurvedic interventions are well tolerable and beneficial in reducing the symptoms of OA knee.

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Published

2025-01-09

How to Cite

Mata, S., Makhija, D., Manathottathil, A., Rana, R. K., Singh, A., Tripathi, A., … Acharya, R. (2025). A community-based study for evaluation of Ayurvedic formulations in the management of Osteoarthritis Knee. International Journal of Ayurvedic Medicine, 15(4), 1029–1036. https://doi.org/10.47552/ijam.v15i4.5021

Issue

Vol. 15 No. 4 (2024): October - December 2024

Section

Research Articles

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