Development, pharmaceutical analysis and invitro evaluation of modified herbal fumigation formulation

Abstract

Ayurveda is science of the life. Maintenance of health of healthy individual and Treatment of diseased are the main principles of ayurveda management. Acharya Sushruta, The Father of Surgery, explained different types of surgeries and documented procedures in sophisticated manner. He also explained Different types of instruments, dressing techniques etc. He clearly emphasized the importance of asepsis in his words Rakshakarma and different drugs he enlisted for it. Rakshakarma includes various karma (procedures) and dhoopan is an important karma among them. In modern, era sterilization and disinfection are the main weapons to deal with the different microbes present in the environment. The incidence of nosocomial infections increasing day by day, thus keeping environment and surfaces microbe free is imperative. Operation theatre is the heart of any surgical hospital and hence its sterilization is of utmost importance. Along with operation theatre complex, fumigation of in-patient and out-patient wards is also necessary. In ayurveda vranitaagar Dhoopan i.e. herbal fumigation of ward is explained by Acharya's. Different ayurvedic herbal, mineral and animal origin drugs explained by acharyas for Dhoopan. To evaluate the efficacy of vranitaagar dhoopan, many researchers are taking efforts and few studies are already completed with promising results. Formaldehyde is most widely used chemical for OT complex fumigation but due to its carcinogenic, irritable properties many safer chemicals are emerging. Still cost effectiveness of these new chemicals is a great hurdle. Formalin is not preferred for routine fumigation of wards. Hence, an attempt is made to modify herbal fumigation formulation for Dhoopan to make ward fumigation effective and safe.