Mushroom Extracts in the Management of Diabetes: A Systematic Review with Special Reference to Oyster Mushrooms

Abstract

A multifactorial metabolic illness with a significant risk of death called diabetes mellitus is defined by elevated blood glucose levels. The quality of life, the health care system, and the economics of nations are all significantly impacted by diabetes and its persistent problems. There are numerous commercial medications available today that are successful in treating hyperglycemia but have several substantial side effects and are unable to appreciably modify the course of diabetes complications. Mushrooms and their bioactive constituents like polysaccharides and terpenoids, are useful in the cure of diabetes mellitus. This systematic review aims to provide an overview of the effects of mushrooms on diabetes. Details on relevant studies were examined using the preferred reporting items for systematic reviews and meta-analyses (PRISMA) norms. Although the mechanism of Pleurotus mushrooms in treating diabetes is still unknown, the anti-diabetic properties of many other species of oyster mushrooms have not been thoroughly researched. More research on edible medicinal mushrooms is required to close the research gap and use their clinical potential to prevent metabolic diseases.