Scientific Basis for the Therapeutic Uses of Semecarpus anacardium Linn. (Bhallataka): A Systematic Review

Abstract

The present review highlights the chemical qualities, therapeutic benefits, toxicity profile of Semecarpus anacardium Linn. (Bhallataka) which is a commonly used plant in Ayurvedic medicine. While there has been some scientific research conducted on the potential therapeutic effects of the plant, more studies are needed to confirm its effectiveness and safety. Due to the generally different approaches taken by each examination, no factual pooling of results or assessment of the nature of the investigations was carried out. Some studies have found that compounds found in Semecarpus anacardium Linn., such as anacardic acid, have anti-inflammatory, antioxidant and anticancer properties. However, further research is needed to understand the full range of therapeutic uses and potential side effects of the plant. Semecarpus anacardium Linn. (Bhallataka) is widely used plant in Ayurvedic medicine, with numerous reported therapeutic benefits. This review provides an overview of the plant's chemical composition, therapeutic effects, and toxicity profile. While some scientific studies have investigated its potential therapeutic effects, further research is necessary to validate its efficacy and safety. Due to the heterogeneity of the studies reviewed, no meta-analysis was conducted. However, several studies have reported that Semecarpus anacardium Linn.  contains compounds, such as anacardic acid, with anti-inflammatory, antioxidant, and anticancer properties. Further research is required to fully elucidate its therapeutic uses and potential side effects. Preliminary research suggests that Bhallataka may have beneficial effects on the cardiovascular system, glucose metabolism, circulatory system, and digestive system, with low toxicity. These findings are promising and support the potential use of Bhallataka as a therapeutic agent.