Evaluating the pharmacokinetics and bioavailability of Pterygota alata inflorescence based on HRMS study to determine the reservoirs of Ayurvedic components with an emphasis on their potential therapeutic use for diabetes mellitus

Abstract

Diabetes indeed requires a comprehensive approach, and dietary changes play a crucial role in managing the condition. While traditional methods like Ayurveda have been used for centuries to address various ailments, including diabetes. Pterygota alata, commonly known as the "winged seed" tree, has been explored for its potential antidiabetic properties in Ayurveda. Research into its efficacy and safety is ongoing, with some studies suggesting promising results. As with any herbal remedy, individuals with diabetes must consult healthcare professionals before incorporating them into their treatment regimen. While herbal products can complement conventional therapies, they should not replace them entirely. Additionally, potential interactions with other medications and individual variations in response should be carefully considered. Through UHPLC-Q-TOF-MS/MS system major antidiabetic component such as Agmatine, Migitol, Trigoneline, Betaine, Theophylline, Quercetin, Kaempferol, Isoliquiritigenin, Esculetin, Rutin, Ferulic acid, Eriodictyol, Naringenin, Luteolin, Salsonilon, Apigenin, Hesperitine, Carvone, Ursolic acid, Betulin, Lupeol, Eugenol.