Assessment of Quality Parameters and Identification of Garcinol in Vrikshamla (Garcinia indica) Using HPTLC- An Analytical Study
DOI:
https://doi.org/10.47552/ijam.v16i3.5807Keywords:
Vrikshamla, Garcinia indica, Garcinol, Quality control, Ayurvedic medicine, HPTLC, Bioactive Compounds, Anti-inflammatory, Anti-obesity, Pharmacological propertiesAbstract
The tropical evergreen tree Vrikshamla (Garcinia indica Linn.), commonly referred to as kokum, has many health advantages, such as anti-inflammatory, anti-obesity, and antioxidant qualities. It contains bioactive substances with therapeutic uses for diseases like Dyslipidemia, cancer, diabetes, and cardiovascular disorders, such as anthocyanins, hydroxycitric acid, and garcinol. For Vrikshamla capsules to be consistent and effective, quality control and validation are crucial. Material and Methods: Vrikshamla capsules were procured from SDM Ayurveda Pharmacy in Udupi. Organoleptic, physicochemical (water-soluble extract, alcohol-soluble extract, pH, loss on drying, and heavy metals), microbiological characteristics and High Performance Thin -Layer Chromatography (HPTLC) were the main focus of the quality analysis, which was carried out in the Central Research Facility in accordance with in-house standard values requirements. Results: High water-soluble (94.71%) and alcohol-soluble (87.77%) extracts with a pH of 3.89 that fell within the normal range were shown by the physiochemical examination. After drying, the heavy metals were in compliance (≤20 ppm), and the loss was 1.12%. The absence of pathogens such as Salmonella spp., P. aeruginosa, and E. coli was verified by microbiological testing. Garcinol's existence in the sample was confirmed by HPTLC analysis, which detected it at Rf 0.63. Discussion: According to the findings, Vrikshamla capsules are of a high calibre, and their pharmacological qualities are attributed to active ingredients like garcinol. Its application in the treatment of metabolic and chronic disorders is supported by its anti-inflammatory, anti-obesity, and neuroprotective properties. Conclusion: Vrikshamla capsules therapeutic value, especially for dyslipidemia, obesity, and inflammation, is confirmed by quality control and validation, underscoring its significance in Ayurvedic medicine.
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