A Randomized Controlled Clinical Study on the Effect of Swarnaprashan (Gold Electuary) on Serum IgG, Anthopometry, and Morbidity Status in Children in Recurrent Upper Respiratory Tract Infections (URTI)

Abstract

Background: Recurrent upper respiratory tract infections (URTIs) in children represent a major public health concern, especially in developing countries. These infections are among the leading causes of morbidity in immunocompromised and susceptible pediatric populations. In India, respiratory infections contribute to nearly 15% of deaths occurring during infancy and childhood. Aim of the study:  To study the Effect of Swarnaprashan (Gold Electuary) on Serum IgG, Anthopometry, and Immune status in Children. Methods: A randomized, open-label clinical study was conducted on 120 children aged 6 to 12 years of both sexes, having low immunity and frequent upper respiratory tract infections. Participants were randomly allocated into two groups of 60 each. Group A received the trial drug SP, while Group B was administered Madhu and Ghrita as the control for a duration of two months. Evaluation Parameters: The study parameters included the incidence of recurrent upper respiratory tract infections (URTI) as reported by participants, the duration and severity of each episode, serum IgG levels, and anthropometric measures. Results: Group A showed significant improvement in morbidity scores(<0.0001), and serum IgG levels (0.0424) whereas Group B demonstrated insignificant changes (>0.05). Conclusion: This clinical trial indicates that SP may serve as an effective intervention for enhancing immune status, reducing the recurrence of upper respiratory tract infections, and promoting the overall growth of children.