Effect of Aparajita (Shweta) Clitoria Ternatea roots with ghrita in the management of Galaganda (Hypothyroidism) wrt Garavisha: A case study

Abstract

In Ayurveda, a closely related condition known as Galaganda (Hypothyroidism)^, is described, rooted in vitiation of Kapha-Vata dosha, Agnimandya (impaired metabolic fire), and Dhatudushti (tissue derangement). Modern management largely depends on synthetic hormone replacement, which addresses symptoms but often fails to correct underlying systemic imbalances. This 80-day case study explores the Ayurvedic management of hypothyroidism using Aparajita Shweta (Clitoria ternatea Linn.) root powder administered with Ghrita (clarified butter) A classical Ayurveda combination to combat above condition mentioned in Yogartnakar. The intervention focused on correcting Doshic imbalance, enhancing Agni, and detoxifying Aama and Garavisha influences. A marked improvement was observed in both subjective symptoms (fatigue, swelling, skin dryness) and objective markers such as weight and TSH level, which reduced from 14.47 µU/mL to 7.17 µU/mL. Clinical grading showed significant reduction in neck swelling and associated discomfort. The findings emphasize the herb’s Shothahara (anti-inflammatory), Kanthya (beneficial for throat disorders), Vishaghna (detoxifying), Agnideepana (digestive fire enhancing), and Medhya (nootropic) properties, suggesting a promising Ayurvedic approach for the management of Galaganda(Hypothyroidism), particularly in cases attributed to Garavisha-janya Galaganda.A condition resulting from chronic exposure to artificial or incompatible toxins (Garavisha). The use of Ghrita (Cows ghee) as an anupana (therapeutic carrier) significantly enhances the bioavailability and potency of the herbal formulation. Ghrita possesses Yogavahi karma (its unique ability to carry the properties of the substances it is combined with deep into the tissues without altering their nature) supported by Trikatu and Gandharvaharitaki for Agni enhancement, Ama digestion and Vatanulomana.