Unveiling the Physicochemical Properties, Mineral Profile and Hemo-Protective Potential of Acacia Suma

Abstract

Anemia is condition when haemoglobin (Hgb) level is <13.0gm/dL in men and <12.0gm/dL in female. In women blood disorders like anemia, menstruation problems, miscarriage, fetus death, ischemia and stroke all are life threatening problems. The Acacia suma has been reported in Ayurvedic Pharmacopeia of India for traditional role in treatment of blood disorders. The hydroalcoholic extract yield was 9.75% and shown presence of phenols, flavonoides and tannins. The hemolytic assay and osmotic fragility assay were performed and percent hemolysis was analysed as Mean ± SD. Further, mineral content of the extract was determined using flame Atomic Absorption Spectrometry. In phytochemical screening the hydroalcoholic extract of Acacia suma shown presence of carbohydrate, proteins, amino acid, steroids, saponin, flavonoids, alkaloids, tannins and phenols. At concentration 250µl/ml, 150µl/ml and 50µl/ml the extract revealed 24.53 ± 3.92 %, 30.63 ± 4.18 % and 54.66 ± 8.92 percent hemolysis respectively. In mineral calcium was found highest among the elements (390.58 ± 7.39 ppm) followed by zinc (26.488 ± 0.32 ppm) and iron (25.84 ± 0.79 ppm). As concentration increases, extract exhibited significant hemo-protective potential and it could be an effective medicine for the treatment of iron deficiency anemia and hemolytic anemia.