Case Series on the Therapeutic Use of a Vedanasthapana-Based Ayurvedic Anal Suppository in Primary Dysmenorrhea

Abstract

Primary dysmenorrhea is a common gynaecological problem marked by painful menstrual cramps that negatively affect daily activities and quality of life. Conventional treatments may cause side effects, leading to interest in Ayurvedic pain-relieving therapies. Vedanasthapana drugs are traditionally used in Ayurveda to relieve pain. This study aimed to evaluate the effectiveness of a Vedanasthapana-based Ayurvedic anal suppository in managing primary dysmenorrhea. Methods: This was an open-label, prospective pilot study conducted on five women diagnosed with primary dysmenorrhea. Each participant received a 3-gram Vedanasthapana anal suppository twice daily for five days, starting seven days before menstruation, for two consecutive menstrual cycles. Pain severity and symptom relief were assessed using the WaLIDD score, Visual Analogue Scale (VAS), associated symptom scores, and the SF-36 quality-of-life questionnaire. Laboratory tests and ultrasonography were performed to rule out secondary causes of dysmenorrhea. Results: All patients showed a noticeable reduction in menstrual pain after treatment. The mean WaLIDD score decreased from 9.6 before treatment to 3.2 after two treatment cycles. The mean VAS pain score reduced from 7.8 to 3.0. Associated symptoms such as nausea, headache, fatigue, and gastrointestinal discomfort also improved. Quality-of-life scores showed better physical functioning, reduced pain, improved emotional well-being, and overall health. No adverse effects were reported during the study. Discussion: The findings suggest that the Vedanasthapana anal suppository is effective in reducing menstrual pain and associated symptoms in primary dysmenorrhea. The rectal route may provide faster pain relief due to improved absorption and avoidance of first-pass metabolism. The observed improvements in pain scores and quality of life support the potential role of this Ayurvedic formulation as a safe and effective alternative therapy for primary dysmenorrhea.