Effect of aqueous extract of Neem (Azadirachta indica a. Juss) patra pichu in Karnini Yoni Vyapada (Cervical erosion) – A randomised controlled clinical trial

Authors

  • Nayana Bhagat Associate Professor, Department of Prasooti Tantra & Stree Roga, KAHER’s Shri BMK Ayurved Mahavidyalya, Belagavi, Karnataka. India.
  • Laxmikant SD Professor, Department of Shalya Tantra, KAHER’s Shri BMK Ayurved Mahavidyalya, Belagavi, Karnataka. India. https://orcid.org/0000-0003-2153-2447
  • Gayatri Hubli Associate Professor, Department of Prasooti Tantra & Stree Roga, KAHER’s Shri BMK Ayurved Mahavidyalya, Belagavi, Karnataka. India.

DOI:

https://doi.org/10.47552/ijam.v16i3.6439

Keywords:

Karnini Yoni Vyapada, Cervical erosion, Azadirachta indica A. JUSS, Neem, Patra Pichu, Ayurveda, Randomized clinical trial

Abstract

Background: Karnini Yoni Vyapada, correlated with cervical erosion in modern gynecology, presents with symptoms such as excessive vaginal discharge, inflammation, and cervical ectopy. Neem (Azadirachta indica A. JUSS) is known in Ayurveda for its antimicrobial, anti-inflammatory and wound-healing properties. Objective: To evaluate the clinical efficacy of using aqueous Neem leaf extract pichu in Karnini Yoni Vyapada. Materials and Methods: A randomized controlled clinical trial was conducted on 120 women (aged 18–50) diagnosed with Karnini Yoni Vyapada. Participants were divided into two groups (n=60). Group - A received pichu (tampon) soaked in fresh aqueous Neem extract for 7 days after menstruation, over three consecutive cycles. Group - B (control) received standard local Ayurvedic treatment Yonidhavana with Triphala kashaya followed by Jatyadi taila pichu. Clinical symptoms (discharge, itching, and backache) cervical findings were monitored, along with pre- and post-treatment pap smears. Observations and Results: Group – A showed statistically significant improvement (p<0.01) in symptoms and cervical healing compared to the Group – B (control group) with notable reductions in discharge, inflammation and cervical erosion. No adverse effects were observed. Conclusion: Neem based Patra Pichu is a safe, effective, and accessible Ayurvedic intervention for managing Karnini yoni vyapada. Its promising results warrant further validation through larger, multicentre trials with long-term follow-up for broader clinical integration.

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Published

2025-09-30

How to Cite

Bhagat, N., SD, L., & Hubli, G. (2025). Effect of aqueous extract of Neem (Azadirachta indica a. Juss) patra pichu in Karnini Yoni Vyapada (Cervical erosion) – A randomised controlled clinical trial. International Journal of Ayurvedic Medicine, 16(3), 823–828. https://doi.org/10.47552/ijam.v16i3.6439

Issue

Vol. 16 No. 3 (2025): July - September 2025

Section

Research Articles

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