TY - JOUR AU - Chalakh, Sonali AU - Wanjari, Anita AU - Wadnerwar, Nilima PY - 2022/07/08 Y2 - 2024/03/29 TI - Analytical standardization of Shleshmantaka Agad JF - International Journal of Ayurvedic Medicine JA - IJAM VL - 13 IS - 2 SE - Research Articles DO - 10.47552/ijam.v13i2.2758 UR - https://ijam.co.in/index.php/ijam/article/view/2758 SP - 504-507 AB - <p>Background:  To counter-act the action of <em>visa,(poison)</em> ancient <em>Acharyas</em> have mentioned the different types of <em>Agada</em>. Though Acharyas have mentioned various types of potent <em>Agadas</em> in various poisoning conditions, still these <em>Agadas </em>have neither undergone analytical study nor animal experiment. <em>Shleshmantaka  Agad </em>is one of the drug remedy mentioned in <em>Shushrut Samhita, kalpa sthan</em>  used for treatment of snake bite poisoning. Aim: In present work an attempt has been made to standardize <em>Shleshmantaka Agad. </em>Material &amp; Methods: Physicochemical parameter was tested by Loss on drying, Acid insoluble Ash, Total ash value, Water &amp; Alcohol soluble Extractive Value, HPTLC was used for phytochemical analysis. Result: In analytical study of <em>Shleshmantaka Agad</em> obtained value of Loss on drying, Total ash value, Acid insoluble Ash ,Water &amp; Alcohol soluble Extractive Value are 12%, 10%, 2%, 13%, 1% respectively and in HPLC major constitute phytoamines  was detected. Conclusion: Analytical findings   of present study can be considered as reference standard for SA. As <em>Shleshmantaka Agada</em> is a combination of many phyto-constitutes but major constituent are phytoamines which may be possesses anti-snake venom property.</p> ER -